Heartburn Meds Tied to Cancer – Popular Drugs May Mask Risk for Disease

Drugs such as Nexium, Prilosec and Prevacid that control production of stomach acid and treat heartburn, reflux, peptic ulcers and related conditions are some of the most popular medications on the market. But long-term use of these drugs, known as proton pump inhibitors, can have unexpected consequences, a new study shows. Blair A. Jobe and his research team at the University of Pittsburgh School of Medicine say the severity of symptoms for GERD, or gastroesophageal reflux disease, has an inverse relationship with the presence of Barrett’s esophagus, a precursor to a lethal form of esophageal cancer known as adenocarcinoma. The

Do PPIs have long-term side effects?

Do PPIs have long-term side effects? Madison Avenue has given stomach acid a bad name, but it’s really kind of a bum rap. Dip into any physiology textbook, and you’ll find that stomach acid serves several constructive purposes. Pepsin, an enzyme that is essential to the preliminary digestion of protein, needs an acidic environment in the stomach to be effective. The strongly acidic hydrochloric acid pumped out by cells in the lining of the stomach also plays a direct role in the early digestion of some foods. And stomach acidity is a built-in barrier to infection. Long-term use Yet millions